Here are the flies I use most of the time:
Schminnows in white (for snook), in black (for cobia), in chartreuse and in copper. I tie them with either bead chain eyes or gold dumbell eyes, depending on where I want to be in the water column. Mostly tie on 1/0 ro 2/0 hooks. This is a very easy fly to tie and works for a wide variety of fish.
Kwans in both light brown and dark brown, depending on bottom color. These immitate both shrimp and crabs so sometimes I tie in rubber legs. They are fished close to the bottom, so use a weed guard. Usually tie on size 1 or 2 hooks. These are my go to redfish fly when they are tailing.
Gurglers mostly in chartreuse, but also in white. I usually tie these with a fairly long tail. The under body is a medium ice chennile with a sparce overwrap of long estaz to simulate legs. Usually tie on size 1 to 1/0 hooks. These are great speck flies.
Toads in a variety of colors, but black with some red mixed in can be a killer. I sometimes tie them in white or copper and sometimes tie in rubber legs. Depending on what I’m after, they could be on 1/0 to 3/0 hooks.
Of course there are the ussual clousers, deceivers, seaducers, etc., but the four I listed are a little different and well suited to the Tampa Bay area. I rarely fish merkins, because I don’t like casting them and they don’t work any better than kwans. I use gold spoonfly’s occasionally, but I don’t like tying them.
I tie almost everything with synthetic materials. The flies are more durable that way and saltwater fish can be tough on flies.