I do a Bonefish trip every first week in December in Isla Morada. It is, IMHO, the greatest time to chase the ghosts. I fish with Greg Poland http://www.gregpoland.com. Dude, if you are serious about this trip please give me a PM. Where are you staying? If you want something memorable we can hook you up.
There are plenty of guides in the Keys, and I’m sure others will be able to list several. But if you want to try to do a little DIY while you’re there, here’s a link to an article I wrote in American Angler a couple of years ago
one of my buddies swears by this guy and fishes with him for a few days every spring. He’s the type of guide that will keep you out as long as you are willing to fish hard, and has a fondness for chasing sickle tails. http://www.lowerkeysflatsfishing.com