I used to tie a pattern for the smokies that I called the Prince Telli that was, as you can guess, a mash up of a Prince Nymph and a Tellico Nymph. I used black hackle tips for the tail, yellow floss thorax with peacock hurl ribbing, Turkey tail fibers for shell back, white goose biots for wings (like a prince nymph), and a brown hackle collar.
I’d also have ants, parachute adams, humpies, green weenies, BHPT, hoppers, stimulators, copper johns, caddis nymph, royal trude, royal coachman, stone fly nymphs… The nice thing about fishing the smokies is you can get away with big flies (size 12/14/16).