I can only compare those two rods as 6wts, the E2 is for me, a rod able to cast any range well I used it with a Sharkskin 6wt, it was easy to cast 100+ with the backing pulling tight to the reel. It also casts well short and mid ranges. The S4 is for me, a rod with a feeling I like, I prefer it short to medium and not so much at distance, given a choice I would take the S4, on a budget the E2 is way better than what you paying. I guess it also depends where it will slot into your rod range, I have a rod that is better for distance fishing and so would look at a rod to fill the gap, of the two, the E2 is a one rod solution